PGT Testing/NHS/Embryo Glue

Hi ❤️ I really need your advice and to hear your story🙏🏽x I'm turning 36 in February and have mild Endometriosis. I had my 1st egg retrieval which resulted in 9 eggs, 6 fertilised and 3 were frozen and one was ready for a fresh transfer funded through the NHS. The fresh transfer failed and I'm currently losing the embryo from the second frozen transfer. My Doctor has mentioned that the embryos were likely to be genetically abnormal and after doing a lot more research I've realised that the embryos were never tested. The nurse mentioned PGT Testing is not available through the NHS but I'm worried the last two will be the same. I really can't handle going through this another two times. I feel it's so unfair for people to have to go through this without getting their embryos tested first, if that's what they wish. Has anyone had success without getting their embryos tested? Or had two failed rounds and then their 3rd or 4th stick through the NHS. Apparently the NHS has now removed the glue to help the embryo stick from the plan after December. Has anyone had a success story without the embryo glue? ❤️💕
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Sorry to hear. I dont have answers but following as maybe in a similar situ next year. Sending all the luck

@Laura Thank you! Sending you all the luck for next year ❤️

This won’t exactly be the answer you’re looking for however I like to share a different side that it’s not always the embryos like we’re told. I had 7 frozen embryo transfers of 11 embryos, all were untested, I fell pregnant every time but lost the first 6 pregnancies to miscarriages with my 7th pregnancy being my baby girl 💕 out of the 6 miscarriages I had 4 of them were sent of for genetic screening after I lost them, every single one was genetically normal despite my clinic always saying they must have been abnormal due to statistics. We decided to have intensive testing done on me after our 4th miscarriage to try and find answers as to why my body seemed to reject the pregnancies. In relation to embryo glue, I used it on 3 out of my 7 transfers but I still fell pregnant 7 times so I don’t believe it made any difference to me. It was free for us though so we thought why not x

I got two embryos from my first round of ivf on the nhs, untested embryos but good grading. The fresh transfer failed but I’m 32 weeks with the remaining frozen one. The nhs only do pgta testing if you are a carrier of a genetic condition. I am 38 so a couple years older than you, not all embryos will be genetically normal especially when you are a bit older but there is still a high probability that one of them is. Good luck

@Jade it really is the answer I was looking for, thank you so much for sharing your amazing story 💕 I am so happy you have your beautiful baby girl. When you decided to have further tests on yourself was it with the same clinic or somewhere else? Did you find out anything helpful? Xx

@Jen This is so lovely to hear, congratulations on your pregnancy 🩷 I feel comforted with your message, thank you so much, I need to focus and hope for the high probability 🙏🏽

PGT testing isn’t very common in the UK unless you or your partner have specific disorders that you need to ensure won’t be passed on. I had 2 failed transfers and my baby girl was my third. I’m now trying for a sibling, my first transfer ended in a miscarriage and now about to go again. On average it takes 3 transfers to have a live birth.

@Hollie thank you for this information 🙏🏽 You have made me feel a lot more positive 🥰 best of luck and magical baby dust for your second transfer! 🩷💕

Thankyou, we still can’t believe that she’s actually ours to keep forever 💕 We went to a different clinic as mine didn’t offer any testing at all other than a set of bloods and they didn’t agree with us over our plan. They told us to PGT test our embryos after the 4th loss even though when we asked at the beginning and after our 3rd loss we were told there was no point in our case and it was too high risk as our embryos were already frozen. I had a full recurrent miscarriage blood panel, a hysteroscopy, an EMMA and ALICE biopsy and NK cell testing done. These showed that my TSH was out of range, I had raised thyroid peroxidase antibodies and elevated NK cells. All of these fell under ‘immune issues’ and the basic way I understood it was my body recognised my pregnancies as something it needed to fight out which caused me to miscarry xx

Not an NHS patient, I am in the US. But we have transferred 5 tested embryos… none stuck. We have done 3 transfers with untested embryos, 2 resulted in a pregnancy (1 ectopic, 1 is my 3 yr old son) and 1 I am in the ttw for now. Best of luck.

If you wanted to do embryo glue, that’s not that expensive in the grand scheme of things so you could probably add that on if you wanted. However, I suspect the reason the NHS has stopped funding it is because the evidence in favour of it is a bit spotty. https://www.hfea.gov.uk/treatments/treatment-add-ons/hyaluronate-enriched-pre-transfer-culture-medium-eg-embryoglue/ The truth is that only around half of your embryos are likely to be genetically normal and that number drops to about 20% when you hit 40, which is what I was when I did IVF. After one failed transfer and one miscarriage, I decided to have my remaining six embryos tested at a cost of around £3.5k. Two did not survive the hatching and thawing process. Two were abnormal and two were normal. The next transfer was another fail and then I finally fell pregnant with our 8th and final embryo. If you do decide to go down the testing route, just bear in mind that most or all of your embryos may end up not being useable.

@Sara k Thank you so much for sharing your experience. I'm really wishing you the best of luck for your tww. 💕 When is your test date? I'm currently in my tww as well but I've been bleeding heavily like my normal period, my test date is 4th December.

@Sharon thank you for your advice and for the link I'm going to check it out and thank you so much for sharing your experience. I'm happy to read that you have your baby boy 💙

@Jade it's such a powerful feeling when you finally understand your body, it does take a lot of tests unfortunately but it's worth the journey, especially when you have your beautiful baby at the end of it all 😃💕xx

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